Gao Liang



Personal profile

Name: Gao Liang


Gender: Female


Degrees: Ph.D


Title: Associate Professor


E-mail: gaoliang@bjut.edu.cn


Current Professional Societies:

1.Member of China Chemical Society

2.Member of the Chinese Society of Biophysics

Research Areas:

1. Developing metal cluster probe system and in situ analytical method by mass spectrometry to quantify tumor proteins as biomarkers.

2.Screening of metal clusters or nanoparticles with high therapeutic efficacy, low toxicity and selective catalytic activity as potential metal drugs.


Publications

First author and corresponding author articles

1.An Artificial Metalloenzyme for Catalytic Cancer-Specific DNA Cleavage and Operando Imaging. Sci. Adv. 2020, 6, eabb1421.

2.Is GSH Chelated Pt Molecule Inactive in Anti-Cancer Treatment? A Case Study of Pt6GS4. Small 2020, 16, 2002044.

3.The Precise Diagnosis of Cancer Invasion/Metastasis via 2D Laser Ablation Mass Mapping of Metalloproteinase in Primary Cancer Tissue. ACS Nano 2018, 12, 11139.

4.Peptide-Au Clusters Induced Tumor Cells Apoptosis via Targeting Glutathione Peroxidase-1: The Molecular Dynamics Assisted Experimental Studies. Sci. Rep. 2017, 7, 131.

5.Peptide Protected Gold Clusters: Chemical Synthesis and Biomedical Applications. Nanoscale 2016, 8, 12095.

6.Peptide-Conjugated Gold Nanoprobe: Intrinsic Nanozyme-Linked Immunsorbant Assay of Integrin Expression Level on Cell Membrane. ACS Nano 2015, 9, 10979.

7.Plasmon-Mediated Generation of Reactive Oxygen Species from Near-Infrared Light Excited Gold Nanocages for Photodynamic Therapy in Vitro. ACS Nano 2014, 8, 7260.

8.Positively Charged Graphene Oxide Nanoparticle: Precisely Label the Plasma Membrane of Live Cell and Sensitively Monitor Extracellular pH in Situ. Chem. Commun. 2014, 50, 3695.

9.Hypocrellin-Loaded Gold Nanocages with High Two-Photon Efficiency for Photothermal/Photodynamic Cancer Therapy in Vitro. ACS Nano 2012, 6, 8030.

10.PH- and Redox-Responsive Polysaccharide-Based Microcapsules with Autofluorescence for Biomedical Applications. Chem. Eur. J. 2012, 18, 3185.

11.Selective Recognition of Co-assembled Thrombin Aptamer and Docetaxel on Mesoporous Silica Nanoparticles against Tumor Cell Proliferation. Chem. Eur. J. 2011, 17, 13170.

Personal Statement

Gao Liang is the associate professor and doctoral supervisor of the College of Chemistry and Biology, Faculty of Environment and Life Science, Beijing University of Technology. Up to now, she has published 14 SCI-index papers as either the lead author or corresponding author. Her 8 papers were published in the journal with impact factors of 5.0, including Sci. Adv., ACS Nano, Small, Nanoscale, Chem. Commun., Chem. Eur. J., which were cited 600 times by other scientists. Besides, she also obtained one invention patent. She also presided 2 projects funded by the National Natural Science Foundation of China and one project by the Beijing Municipal Education Commission.