Ren Xiaojun

Personal profile

Name:Ren Xiaojun



Title:Assistant Research Fellow

Research Areas

  1. Single cell analytical chemistry based on fluorescence and mass spectrometry;

  2. Nucleic acid imaging and detection technologies;

  3. Biological imaging based on large scientific device synchronous light source


  1. Xiaojun Ren, Kaixiang Zhang, Ruijie Deng, Jinghong Li*,RNA splicing analysis: from in vitro testing to single-cell imaging,Chem, 2019, 5, 2571-2592,

  2. Xiaojun Ren, Ruijie Deng, Kaixiang Zhang, Xucong Teng, Yupeng Sun and Jinghong Li*. SpliceRCA: in situ single-cell analysis of mRNA splicing variants.ACS Cent. Sci., 2018, 4, 680-687

  3. Xiaojun Ren, Ruijie Deng, Lida Wang, Kaixiang Zhang and Jinghong Li*. RNA splicing process analysis for identifying antisense oligonucleotide inhibitors with padlock probe-based isothermal amplification.Chem. Sci.2017, 8, 5692-5698

  4. Xiaojun Ren, Shizheng Wang, Dongdong Su, Liang Gao, Qing Yuan, Xueyun Gao*,Noble-metal nanocluster as enzyme-mimetic catalyst for diagnostic analysis,SCIENCE CHINA Technological Sciences, 2019, 62, 2306–2309,

  5. Xiaojun Ren, Haihong Bai, Yiting Pan, Wei Tong, Rugang Zhong, Weijie Qin, Xiaohong Qian. A graphene oxide-based immobilized PNGase F reagent for highly efficient N-glycan release and MALDI-TOF MS profiling.Analytical Methods.2014, 8, 2518-2525

  6. Ruijie Deng, Kaixiang Zhang, Lida Wang,Xiaojun Ren, Yupeng Sun and Jinghong Li* DNA-Sequence-Encoded Rolling Circle Amplicon for Single-Cell RNA Imaging.Chem. 2018, 4,1194-1196

  7. Yupeng Sun, Ruijie Deng, Kaixiang Zhang,Xiaojun Ren, Ling Zhang and Jinghong Li*. Single-cell study of extracellular matrix effect on cell growth by in situ imaging of gene expression.Chem. Sci. 2017, 8, 8019–8024

  8. Ruijie Deng, Kaixiang Zhang, Yupeng Sun,Xiaojun Renand Jinghong Li*. Highly specific imaging of mRNA in single cells by target RNA-initiated rolling circle amplification.Chem. Sci.2017, 8, 3668-3675.

  9. Yupeng Sun, Kaixiang Zhang, Ruijie Deng,Xiaojun Ren, Can Wu and Jinghong Li*. Tunable stiffness of graphene oxide/polyacrylamide composite scaffolds regulatescytoskeleton assembly.Chem. Sci., 2018, 9, 6516–6522

  10. Kaixiang Zhang, Ruijie Deng, Xucong Teng, Yue Li, Yupeng Sun,Xiaojun Ren, and Jinghong Li*. Direct Visualization of Single-Nucleotide Variation in mtDNA Using a CRISPR/Cas9-Mediated Proximity Ligation Assay.J. Am. Chem. Soc.2018, 140, 11293-11301

  11. Xin Tang, Ruijie Deng, Yupeng Sun,Xiaojun Ren, Mengxi Zhou and Jinghong Li*. Amplified Tandem Spinach-Based Aptamer Transcription Enables Low Background miRNA Detection.Anal. Chem. 2018, 90, 10001-10008.

  12. Ruijie Deng, Yi Dong, Xuhan Xia, Yicong Dai, Kaixiang Zhang, Qiang He, Wei-cai Zeng,Xiaojun Ren, and Jinghong Li*. Recognition-enhanced metastably shielded aptamer (RMSApt) enables digitally quantifying small molecules.Anal. Chem.2018, 90, 14347-14354

  13. Yupeng Sun, Ruijie Deng,Xiaojun Ren, Kaixiang Zhang, and Jinghong Li*. 2D Gelatin Methacrylate Hydrogels with Tunable Stiffness for Investigating Cell Behaviors.ACS Appl. Bio Mater., 2019, 2, 570–576

  14. Ya Zhang, Xiangchun Zhang, Qing Yuan, Wenchao Niu, Chunyu Zhang, Jiaojiao Li, Zhesheng He, Yuhua Tang,Xiaojun Ren, Zhichao Zhang, Pengju Cai, Liang Gao * and Xueyun Gao*. Peptide-Templated Gold Clusters as Enzyme-Like Catalyst Boost Intracellular Oxidative Pressure and Induce Tumor-Specific Cell Apoptosis.Nanomaterials, 2018, 8, 1040

  15. Haihong Bai, Yiting Pan,Xiaojun Ren, Feiran Hao, Hui Yan, WeiJie Qin, Xiaohong Qian. An Ultra-fast and Highly Efficient Multiple Proteases Digestion Strategy Using Graphene Oxide-Based Immobilized Protease Reagents.Science China Chemistry.2014, 5, 695-707.

  16. Haihong Bai, Yiting Pan, Wei Tong, Wanjun Zhang,Xiaojun Ren, Fang Tian, Xin Wang, Yangjun Zhang, Yulin Deng, Weijie Qin, Xiaohong Qian. Graphene Based Soft Nanoreactors for Facile "One-Step" Glycan Enrichment and Derivatization for MALDI-TOF-MS Analysis.Talanta.2013, 15, 1-7.

  17. Hui Yan, Feiran Hao, Qichen Cao, Jiabin Li, Nannan Li, Haihong Bai,Xiaojun Ren, Xianyu Li, Yangjun Zhang, Xiaohong Qian. A Novel Method for Identification and Relative Quantification of N-terminal Peptides Using Metal Element Chelated Tags Coupled with Mass Spectrometry.Science China Chemistry.2014, 5, 708-717.

Personal Statement

Ren Xiaojun,MasterStudentSupervisor, has got her doctoral degree in Analytical Chemistry from Beijing Institute of Technology, and simultaneously co-cultivated in the Department of Chemistry of Tsinghua University. She has presided over projects of National Natural Science Foundation of China, Beijing Municipal Natural Science Foundation, China Postdoctoral Science Foundation and Beijing Postdoctoral Research Foundation etc..