þ Master Supervisor

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Current Professional Societies

1. Young Editorial Board Member of <Exploration>

2. Member of China Chemical Society

3. Member of Chinese Society of Micro-Nano Technology

Research Areas

1. Design of ultra small metal nanomaterials with immunoregulatory activities

2. Treatment and prevention of immunological diseases via metal nanomaterials, including neurodegenerative diseases, autoimmune diseases and cancer, etc.

Publications（First Author or Corresponding Author）

1. Parkin inhibits necroptosis to prevent cancer, Nat Cell Biol, 2019,21(8): 915-16.

2. Mitochondrial dynamics regulate genome stability via control of caspase-dependent DNA damage, Dev Cell，2022,23;57(10):1211-1225.

3. Colon-Accumulated Gold Nanoclusters Alleviate Intestinal Inflammation and Prevent Secondary Colorectal Carcinogenesis via Nrf2-Dependent Macrophage Reprogramming. ACS Nano. 2023,17(18):18421-32.

4. Environmental Low-Dose Radiation Activates Th1 Immunity through the Mitochondria-STING Pathway. Environ Sci Technol. 2024, 31;58(52):22907-22918.

5. Targeted Gold Nanoclusters for Synergistic High-Risk Neuroblastoma Therapy through Noncanonical Ferroptosis. ACS Appl Mater Interfaces. 2024, 9;16(40):53555-53566.

6. Histone deacetylase inhibitors prevent activation-induced cell death and promote anti-tumor immunity. Oncogene. 2015,34(49):5960-70.

7. Clusterbody Enables Flow Sorting-Assisted Single-Cell Mass Spectrometry Analysis for Identifying Reversal Agent of Chemoresistance, Anal Chem, 2023,17;95(2):560-564.

8. Interleukin-17 promotes nitric oxide-dependent expression of PD-L1 in mesenchymal stem cells, Cell Biosci, 2020,10(73).

9. Recent advances in nanotechnology for programmed death ligand 1-targeted cancer theranostics. J Mater Chem B. 2024,27;12(13):3191-3208.

10. Disturbing microtubule-endoplasmic reticulum dynamics by gold nanoclusters for improved triple-negative breast cancer treatment. J Mater Chem B. 2024, 20;12(45):11648-11658.

11. Apoptosis and Cancer: Force Awakens, Phantom Menace, or Both? Int Rev Cell Mol Biol. 2018,337:135-152.

12. Induction of Non-Canonical Ferroptosis by Targeting Clusters Suppresses Glioblastoma. Pharmaceutics. 2024, 13;16(9):1205.

Personal Statement

Cao Kai is the associate professor, master supervisor and the international youth supervisor in the College of Chemistry and Life Science, Beijing University of Technology. He got his Ph. D. degree from the University of Chinese Academy of Sciences (UCAS) and was a research associate in the Beatson Institute Cancer Research UK in Glasgow. Up to now, he has published 12 SCI-index papers as either the lead author or corresponding author. All of them were published in JCR Q1 journals. He also presided one project funded by the National Natural Science Foundation of China and one project by the Natural Science Foundation of Beijing.