þ Master Supervisor

Current Professional Societies

Youth Editorial Board Member ofJournal of Analysis and Testing

Research Areas

Microfluidics, Single-cell analysis, microphysiological system

Honors

2019, The Best poster award in "Microfluidics and flow Chemisty 2019 Conference" California, USA, 8th October, 2019

2016, "Zhao-Lun Fang Young Researcher Lecture Award" on 2016 International Conference on Microfluidic chip and Micro/nano Scale Bioseparation Analysis (2016, Lanzhou)

2012, The best poster award in "The 3rd International Conference on Advances in Microfluidics & Nanofluidics (AMN2012)"

2010, 2010 Eli Lilly Asia Outstanding Graduate Thesis Award. Awarded by the Eli Lilly and company. One of 22 winners in Asian

Publications

1.L. Zhao, X. Wang*, 3D printed microfluidics for cell biological applications. Trends Anal. Chem. 2023, 158, 116864.

2. M. Shi, L. Wang, Z. Xie,L. Zhao*, X. Zhang*, M. Zhang*, High-Content Label-Free Single-Cell Analysis with a Microfluidic Device Using Programmable Scanning Electrochemical Microscopy. (supplementary cover) Anal. Chem. 2021, 93, 12417−12425.

3.L. Zhao*, Y. Liu, Y. Liu, M. Zhang, X. Zhang*, Microfluidic Control of Tumor and Stromal Cell Spheroids Pairing and Merging for Three-Dimensional Metastasis Study. Anal. Chem. 2020, 92, 11, 7638–7645.

4. Y. Liu, Y. Liu, X. Zheng, L.Zhao*, X. Zhang*, Recapitulating and Deciphering Tumor Microenvironment by Using 3D Printed Plastic Brick–Like Microfluidic Cell Patterning. Adv. Healthcare Mater. 2020, 1901713.

5. Z. Feng, D. Wang, Y. Zheng*,L. Zhao*, T. Xu, Z. Guo, M. Hussain, J. Zeng, L. Lou, Y. Sun, H. Jiang, A novel waterborne polyurethane with biodegradability and high flexibility for 3D printing. Biofabrication, 2020, 12, 035015.

6. L. Zhao*, J. Xiu, Y. Liu, T. Zhang, W. Pan, X. Zheng, X. Zhang*, A 3D Printed Hanging Drop Dripper for Tumor Spheroids Analysis Without Recovery. Sci. Rep. 2019, 9, 19717.

7. Z. Feng, Y. Zheng*,L. Zhao*, Z. Zhang, Y. Sun, K. Qiao, Y. Xie, Y. Wang, W. He, An ultrasound-controllable release system based on waterborne polyurethane/chitosan membrane for implantable enhanced anticancer therapy. Mater. Sci. & Eng. C. 2019, 104, 109944.

8. J. Xiao, Y. Liu, L. Su*, D. Zhao,L. Zhao*, X. Zhang*, Microfluidic Chip-Based Wearable Colorimetric Sensor for Simple and Facile Detection of Sweat Glucose. (supplementary cover) Anal. Chem. 2019, 91, 23, 14803-14807.

9. H. Qiao, T. Guo, Y. Zheng*,L. Zhao*, Y. Sun, Y. Liu, Y. Xie, A novel microporous oxidized bacterial cellulose/arginine composite and its effect on behavior of fibroblast/endothelial cell. Carbohydrate Polymers 2018, 184, 323-332.

10. L. Zhao*, M. Shi, Y. Liu, X. Zheng, J. Xiu, Y. Liu, L. Tian, H. Wang, M. Zhang*, X. Zhang*, Systematic Analysis of Different Cell Spheroids with a Microfluidic Device Using Scanning Electrochemical Microscopy and Gene Expression Profiling. Anal. Chem. 2019, 91, 4307-4311.

11. L. Zhao*,T. Guo, L. Wang, Y. Liu, G. Chen, H. Zhou, M. Zhang*, Tape-Assisted Photolithographic-Free Microfluidic Chip Cell Patterning for Tumor Metastasis Study. Anal. Chem. 2018, 90, 777−784.

12. H. Zhou,L. Zhao*, X. Zhang*, In-Channel Printing-Device Opening Assay for Micropatterning Multiple Cells and Gene Analysis. Anal. Chem. 2015, 87, 2048−2053.

13. A. M. Streets, X. Zhang, C. Cao, Y. Pang, X. Wu, L. Xiong, L. Yang, Y. Fu,L. Zhao*, F. Tang*, Y. Huang*, Microfluidic single-cell whole transcriptome sequencing. Proc. Natl. Acad. Sci. USA 2014, 111, 7048-7053.

14. C. Zheng^#,L. Zhao^#, G. Chen, Y. Zhou, Y. Pang, Y. Huang*, Quantitative Study of the Dynamic Tumor–Endothelial Cell Interactions through an Integrated Microfluidic Coculture System. (#equally contribution), Anal. Chem., 2012, 84, 2088-2093.

Books

Microfluidics: Fundamentals, Devices, and Applications. Wiley-VCH; (January 4, 2018). ISBN: 9783527341061. Authors: Yujun Song, Daojian Cheng, Liang Zhao.

Personal Statement

In the realm of life sciences, the advent of microfluidic technology has heralded a new era of precision and efficiency. My fascination with this field stems from its transformative potential in unraveling the intricacies of biological systems at the nanoliter scale. The ability of microfluidic chips to conduct chemical or biological experiments with unparalleled spatial and temporal control captivates my scientific curiosity. This technology not only aligns with the scale compatibility of mammalian cells but also seamlessly integrates with imaging processes, offering a versatile platform for cell manipulation and automation. My academic journey and research experiences have progressively steered my interests toward the exploration of biological analysis using microfluidic devices. The prospect of coupling microfluidic systems with advanced analytical techniques such as chromatography, 3D printing, and single-molecule experiments excites me. These integrations promise a comprehensive understanding of cellular behaviors and mechanisms at an individual level, which conventional bulk analysis methods are usually difficult to achieve. My ambition is to contribute to this cutting-edge field by developing innovative microfluidic platforms that can facilitate detailed quantitative biological studies.